Principles of antibiotic therapy in surgical practice. What should a practitioner not forget about?

The rational use of antimicrobial drugs in surgery includes the correct choice of drug, its timely administration, minimizing the duration of therapy and switching to oral forms, regular monitoring and use of microbiological research data. These principles help reduce the risk of infections, minimize side effects, and prevent the development of antibiotic resistance. This article reviews basic information about the principles of rational initiation of antibiotic therapy, perioperative antibiotic prophylaxis, the rational choice of an antibacterial drug, the dose of the antibiotic, the mode of administration, and the optimal therapy duration.