Future directions in flow biocatalysis: The impact of new technology on sustainability

Flow chemistry is now a key technology for synthetic chemistry, with the different operating windows available allowing new chemistry to be optimised and discovered. The related area of flow biocatalysis is also becoming increasingly recognised as an integral aspect of bioprocess optimisation, with modularisation and technology integration some of the key drivers for this. This minireview will discuss some recent examples where flow has substantially improved the sustainability of a bioprocess. We also reflect on the increase in analytics, how it is starting to impact bioprocess optimisation, and what the implications of this will be moving forward.