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June 28, 2024iScienceOpen Access

SPI1-KLF1/LYL1 axis regulates lineage commitment during endothelial-to-hematopoietic transition from human pluripotent stem cells

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Authors

KQKengyuan QuSMShaokang MoJHJunfeng Huang

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Cite This Study

Qu et al. (2024) studied this question.

synapsesocial.com/papers/68e62c14b6db6435875be151https://doi.org/10.1016/j.isci.2024.110409
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1LSD1/KDM1A and GFI1B repress endothelial fate and induce hematopoietic fate in induced pluripotent stem cell-derived hemogenic endotheliums2024
  2. 2Transcriptional Activity of Erythroid Kruppel-like Factor (EKLF/KLF1) Modulated by PIAS3 (Protein Inhibitor of Activated STAT3)2015 · 9 citations
  3. 3LYL1 is critical for adult hematopoietic stem cell-derived B and T lymphopoiesis2025
  4. 4Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors2024 · 1 citations
  5. 5EKLF/KLF1 coordinates specialized transcriptional networks required to maintain the integrity of terminal erythropoiesis2025