The review considers the possibility of using various cryomethods, as well as technologies for cryopreservation of biological objects for their implementation in medical practice, including the treatment of patients with purulent wounds that do not heal for a long time – PWNHLT. Attention is paid to a wide range of methodological and methodological approaches to the use of cold factor in medical practice: general and local cryotherapy, cryosurgery, etc. Each of these methods is considered as an element of the start of regenerative processes, including the healing of PWNHLT. Particular attention in the work is paid to cryotechnologies that ensure the preservation at low temperatures of various biological objects, namely cord blood. It is indicated that its therapeutic effect (cells, serum) has a multi-vector direction, including immunomodulatory and trophic stimulation, which is extremely important in the treatment of patients with PWNHLT. The issue of combined use of cord blood serum and innovative VAC-therapy in the treatment of PWNHLT is considered.
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Goltsev et al. (2024) studied this question.
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