Formulation And Evaluation of Preparations Edible Film Combination Gingerol And Curcumin As An Antibacterial Streptococcus pyogenes Causes Of Inflammation Of The Throat

Ginger (Zingiber officinale) and turmeric (Curcuma longa L) are wellknown herbal plants appreciated for their therapeutic advantages.These botanicals consist of bioactive elements referred to as gingerol and curcumin, respectively, which display potential antibacterial qualities.The purpose of this study was to obtain an edible film combination of gingerol and curcumin that met the evaluation requirements and had antibacterial activity against Streptococcus pyogenes.The study employed the solvent casting method, evaluating the edible film through sensory analysis, thickness measurement, weight uniformity, pH, folding resistance, friability, water content, elongation and tensile strength, disintegration and dissolution time analysis, stability examination, hedonic testing, antibacterial activity evaluation against Streptococcus pyogenes bacteria, and functional group analysis.The outcomes of the research revealed that edible films had rectangular shapes measuring 2x3 cm with different colors for each formulation, sweet and spicy taste, distinctive smell, and the evaluation results meet the appropriate requirements of Japanese Industrial Standards (JIS) and existing theories, but the percent elongation has poor results.Then, edible film single and combination formulations were able to inhibit bacteria with diameters of inhibition zones F2 6.56 mm ± 0.6325, F3 6.36 mm ± 0.0748, and F4 6.92 mm ± 0.0920 against Streptococcus pyogenes bacteria with respectively medium category.