Chronic Prostatitis and Chronic Pelvic Pain Syndrome – the Current State of the Problem

The objective: to conduct an analysis of contemporary research data devoted to the study of the pathogenesis, diagnosis, and treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), evaluate its manifestations according to the UPOINT classification and the NIH-CPSI scale, and present our own experience in applying the NIH-CPSI scale and UPOINT classification in clinical practice. Materials and methods. A literature search was conducted in scientific databases using keywords such as «chronic prostatitis», «chronic pelvic pain syndrome», «pathophysiology», «diagnosis», and «treatment». A total of 25 patients with CP/CPPS were examined to demonstrate the clinical utility of the NIH-CPSI scale and UPOINT classification. Results. The literature review represented main theories of pathogenesis and approaches to the diagnosis and treatment of CP/CPPS. Additionally, clinical data demonstrated that the average NIH-CPSI score among patients with CP/CPPS was 26.8±6.8 points. According to the UPOINT classification, the urinary domain was present in 88.0% of patients, psychosocial domain in 68.0%, organ-specific domain in 48.0%, infectious domain in 32.0%, neurological domain in 24.0%, and muscle tension domain in 12.0% of patients. Conclusions. Phenotyping based on the UPOINT classification along with the NIH-CPSI scale can be utilized in patients to assess and guide multimodal treatment for CP/CPPS.