Procedural Sedation in Regional Anaesthesia – Narrative Review

Background: Regional anesthesia is a widely utilized technique. Supplementing the regional anesthesia with the sedatives will lessen the patient’s anxiety while increasing the effectiveness of various blocks. we evaluated hemodynamic changes, level of sedation, and level of satisfaction of both the surgeon and patient when regional anesthesia is supplemented with sedatives like Ketamine, Propofol, and Dexmedetomidine. Aim: The main aim of the study is to know the hemodynamic changes, level of sedation, and level of satisfaction of both the surgeon and patient when regional anesthesia is supplemented with sedatives. Methods: An extensive search of all materials related to the topic with keywords - Intraoperative sedation, Analgesia, Regional block, and Sedatives was carried out in the PubMed and Google Scholar Search engines. over 79 articles were identified on this topic including original research articles. Among these 15 articles were excluded as they did not match the field of our review and 21 articles were excluded as full articles were not available for review. Thus relevant research articles focusing on “Procedural sedation in regional Anaesthesia” published in the period 2000 – 2021 were included in the review. A total of 10 studies similar to the current study objectives were included in the study and analyzed. Conclusion: After reviewing the literature, we conclude that Propofol in combination with Ketamine given intravenously is a good substitute for procedural sedation along with regional anesthesia technique. When supplemented with regional anaesthesia, it is found to provide better hemodynamic stability intraoperatively and better surgeon and patient satisfaction.