Abstract Endometriosis (EMS) refers to the appearance, growth and infiltration of endometrial tissues (glands and stroma) in the uterine cavity covering the endometrium and other parts of the uterus, repeated bleeding, Rare pelvic and intraperitoneal endometriosis can invade various areas such as the pleura, lungs, groin, umbilical cord, diaphragm, sciatic nerve, external ear, scalp, etc.Thoracic endometriosis syndrome (TES) is a rare disorder characterized.It can be divided into pleural and pulmonary endometriosis (PEM)according to the site of the lesion.The pathogenesis of TES has not yet been clarified, and multiple hypotheses have been proposed to explain its pathogenesis and clinical manifestations.The abnormality of the immune system is one of the important factors that cause and promote the occurrence and development of EMS.We report a 32-year-old woman diagnosed at our hospital with PEM presented a clinical characteristic of intermittent cough and hemoptysis and a pathologic manifestation of a large amount of hemosiderin deposition and a small amount of fibrous tissue.The patient was treated with leuprolide combined with tibolone. The patient’s cough and hemoptysis improved significantly within a short period of time, and his lung lesions improved significantly.At the same time,he did not develop serious related complications.Our report suggests that Add-back therapy of the patient’s conditions is necessary in PEM patients with not accepted surgical treatment.Leuprolide combined with tibolone may be an induction therapy with safety and feasibility.However, more clinical trials are needed to validate the efficacy and safety of the therapeutic regimen.
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Ni et al. (2024) studied this question.
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