An Overview of Lean Six Sigma management applications in research animals facilities

Lean Six Sigma (LSS) is recognized as a continuous improvement methodology that enhances operational processes by reducing waste, variability, and costs, while increasing the quality of products and services. Originating in the industrial and manufacturing sectors, it has been implemented in healthcare over the past three decades to improve operational performance, costs and excellence. In animal research facilities, LSS was first reported at Seattle Children’s Hospital, where tools and methods were applied in administrative and research support services. The objective of this study was to characterize the current knowledge regarding the application of LSS tools in animal research facilities, identifying the benefits and limitations of these practices. A database search identified 227 publications, of which 11 were selected. The results showed that LSS has notable applicability and should be incorporated associated with initiatives for cultural and organizational change despite limitations as resistance to implementation and difficulty in sustainment the gains.