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The utilization of Cissus quadrangularis and other medicinal plants in traditional and modern medicine holds promise for the prevention and management of oxidative stress-related maladies. Top of FormThe aim of present work was to assess the free radical scavenging potential of the selected bioactive component of stem extract using different solvent (aqueous, methanol, dichloromethane, acetone and chloroform) of the plant Cissus quadrangularis. Antioxidant activity of the selected phytochemical of stem extract of the plant Cissus quadrangularis were done by Ferric reducing antioxidant power assay, DPPH antioxidant power assay and hydroxyl radical scavenging activity. The analysis of ferric reducing antioxidant power assay indicate that all tested solvent extract have good antioxidant potential as compare to ascorbic acid which was taken as reference. Acetone extract expressed maximum antioxidant potential with EC50 value 0.17 and chloroform extract expressed minimum antioxidant potential with EC50 value 0.35. The order of ferric reducing antioxidant potential among the tested solvent are as s follow: Acetone > Dichloromethane > Methanol > Aqueous > Chloroform. The results of the present study showed that all the extracts exhibited potent antioxidant activity. The analysis of DPPH antioxidant power assay, HRS antioxidant power assay and Ferric reducing antioxidant power assay indicate that all tested solvent extracts have good antioxidant potential and among the five extracts methanolic, dichloromethane, and acetone extract respectively exhibited higher potency of free radical scavenging activity.
Arvind Kumar (Tue,) studied this question.