Successful closure of large mucosal defect with novel anchor-pronged clip after gastric endoscopic submucosal dissection

Delayed bleeding after gastric endoscopic submucosal dissection (ESD) is a major complication [1] that sometimes leads to shock, and mucosal defect closure to prevent delayed bleeding was reported [2]. However, the thickness of the gastric mucosa and proper muscle layer makes suturing difficult [3]. A recent study reported the closure of an intermediate-size mucosal defect post-gastric ESD with a novel anchor-pronged clip (MANTIS Clip; Boston Scientific, Marlborough, Massachusetts, USA) ([Fig. 1]) [4]. Here, we present the successful closure of large mucosal defect with a MANTIS Clip after gastric ESD ([Video 1]).