Adnexal adenocarcinoma is a skin tumor derived from apocrine or eccrine glands, hair follicles, and sebaceous glands. These neoplasms occur most frequently in the head and neck, and present as a single nodule or plaque of varying color.1 By histology, these tumors are often poorly circumscribed, infiltrative, and of heterogeneous composition consisting of tubules, nests, ducts, and glands.1 Rare characteristics include cellular infiltration in a single-file arrangement that resembles metastatic breast cancer (MBC).
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Babkowski et al. (2024) studied this question.
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