Identification of putative α-glucosidase inhibitors and antioxidants in Zingiber officinale rhizome using LCMS-based metabolomics and in silico molecular docking

Metabolite profiling is required to reveal bioactive chemicals in ginger rhizome for supporting its traditional claim as anti-diabetic agent. This study aimed to evaluate α-glucosidase inhibitory (AGI) and antioxidant activities of the rhizome, to identify its putative α-glucosidase inhibitors, and to analyse the protein-ligand interaction of the inhibitors. The ginger extracts were tested to