Iridocorneal endothelial syndrome is a rare disorder characterized by increased proliferation and migration of corneal endothelial cells to the iris and anterior chamber angle, leading to secondary angle-closure glaucoma, corneal edema, and iris atrophy. This condition is often associated with secondary glaucoma due to obstruction of the trabecular meshwork and formation of peripheral anterior synechiae. Vision loss usually occurs due to progression of secondary glaucoma and corneal decompensation.
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Safonova et al. (2024) studied this question.
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