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June 24, 2024Frontiers in AntibioticsOpen Access

Genomic modifications for enhanced antibiotic production in rifamycin derivative-producing Amycolatopsis mediterranei S699 strains: focusing on rifQ and rifO genes

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Authors

MMMoritz MüllerEBElena BialasISIrina Sturm

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Müller et al. (2024) studied this question.

synapsesocial.com/papers/68e63804b6db6435875c9f40https://doi.org/10.3389/frabi.2024.1399139
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Amycolatopsis mediterranei: A Sixty-Year Journey from Strain Isolation to Unlocking Its Potential of Rifamycin Analogue Production by Combinatorial Biosynthesis2024 · 4 citations
  2. 2Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel “unnatural” natural products1999 · 464 citations
  3. 3Construction of a hybrid plasmid capable of replication in Amycolatopsis mediterranei1991 · 44 citations
  4. 4Tolerance and Specificity of Polyketide Synthases1999 · 339 citations