Design and Development of Simvastatin Loaded Liposomes

Liposomes containing simvastatin were the focus of recent research. A process called thin film hydration was used to create simvastatin (SVN) liposomes. Method optimization was accomplished with the help of the BBD model. Drug content, vesicle size, surface shape, and in-vitro drug release were evaluated in the generated liposomes. There was no liposome that did not meet the criteria for appropriate drug content and mean vesicle size. Liposomes that did not combine and had a spherical or nearly spherical shape were seen in the surface morphology. The produced liposomes have demonstrated significant drug release. Liposomes loaded with SVN were successfully manufactured and tested.