An unusual case of oral warty dyskeratoma associated with human papilloma virus

Warty Dyskeratoma (WD), also known as isolated Darier’s disease or focal acantholytic dyskeratosis, is a rare mucocutaneous anomaly and is known as a benign solitary tumor of the skin, vulva, oral cavity. The size of many oral lesions associated with the virus is smaller than 1 cm. An example of such a lesion might be given as squamous papilloma. In such situations, the presence of viral particles will be a distinguishing factor in the case of squamous papilloma lesions. The histological examinations and Polymerase Chain Reaction (PCR) techniques were employed to investigate the potential involvement of Human Papilloma Virus (HPV) infection in the development of Oral Warty Dyskeratoma (OWD). Degenerate primers were utilized for this purpose. The diagnosis of OWD was verified through histopathological investigation, and the presence of HPV DNA was detected through PCR. Currently, the only study found in the literature that has demonstrated the existence of HPV DNA in a case of OWD is by special techniques like PCR. For future research, it would be advantageous to employ sequencing to determine the HPV-DNA.