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The present study explores multi-compartment FDE models with modified conditions for pharmacokinetics of anomalous drug diffusion in Caputo derivative sense.The Adomian decomposition method is implemented for analysis of non-commensurate model to depict the concentration of a single dose of enteric coated drug, in particular, Diclofenac in the blood plasma in two-compartment.Non-linear regression is used for parameter estimation.In the present text, authors validated the model showcasing the best-fit for the experimental in-vivo data from the existing literature to ensure eradication of toxicity and ineffective treatment risk.Statistical analysis is performed using Mathematica to understand significance of each estimated parameter in the regression model.Stability analysis in graphical sense is examined for decision making.The authors have justified existence and uniqueness by Picard-Lindelöf theorem.
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D’Cunha et al. (2024) studied this question.
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