Investigating functional and folding stability of an engineered E. coli L-asparaginase harboring Y176F/S241C mutations

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Nonclinical Evaluation of Single-Mutant E. coli Asparaginases Obtained by Double-Mutant Deconvolution: Improving Toxicological, Immune and Inflammatory Responses2024 · 1 citations
2. 2Protein Bioengineering of a Crucial Biopharmaceutical for Acute Lymphoblastic Leukaemia: Improving Toxicogical, Immune and Inflammatory Responses to Asparaginase2024 · 1 citations
3. 3Production of highly cytotoxic and low immunogenic L-asparaginase from Stenotrophomonas maltophilia EMCC22972024 · 2 citations
4. 4<i>In Silico</i>-Driven Engineering of<i>Halomonas elongata</i>L-Asparaginase: Towards Enhanced Proteolytic Resistance in Lymphoblastic Leukemia2024
5. 5Recombinant expression and preliminary characterization of a synthetic L‐asparaginase from the marine bacterium Pseudoalteromonas tetraodonis GFC in Escherichia coli BL21 (DE3)2026