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June 21, 2024Archiv der PharmazieOpen Access

Design, synthesis, and antiproliferative activity of new indole/1,2,4‐triazole/chalcone hybrids as EGFR and/or c‐MET inhibitors

Esraa Mahmoud Dalia Abdelhamid Bahaa G. M. Youssif Hesham A. M. Gomaa Alaa M. Hayallah Mohamad Abdel‐Aziz

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Abstract

A novel group of indolyl-1,2,4-triazole-chalcone hybrids was designed, synthesized, and assessed for their anticancer activity. The synthesized compounds exhibited significant antiproliferative activity. Compounds 9a and 9e exhibited significant cancer inhibition with GI

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Mahmoud et al. (2024) studied this question.

synapsesocial.com/papers/68e63c11b6db6435875cdf82 https://doi.org/10.1002/ardp.202300562

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