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June 21, 2024BMC Infectious DiseasesOpen Access

Genetic variation of TLR3 gene is associated with the outcome of hepatitis b infection in mauritanian patients: case control study

Tetou Soumbara Crystel Bonnet Cheikh Tijani Hamed Fatimetou Veten Mohamed Hemeyine F‐Zahra Fall‐Malick Mohamed Mahmoud El Yezid Adama Diallo Moustapha Mouhamedou Mounah Ahmed Houmeida

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Abstract

Toll-Like receptors (TLRs) play an important role in the immune response during hepatitis B virus (HBV) infection. In this study, we evaluated the association between two SNP variants (TLR3 rs3775290 and TLR4 rs4986790) and susceptibility to chronic HBV infection in Mauritania.

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Soumbara et al. (2024) studied this question.

synapsesocial.com/papers/68e63c23b6db6435875ce5db https://doi.org/10.1186/s12879-024-09503-w

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Polymorphism of the TLR3 gene in Predisposition to Chronic Viral Hepatitis B and C in the population of Turkic-speaking peoples2024
2Association of polymorphisms in TLR3 and TLR7 genes with susceptibility to COVID-19 among Iranian population: a retrospective case-control study2024 · 4 citations
3Association of genetic variations in Toll-Like receptor 3 with Acute Lymphoblastic leukemia2024 · 1 citations
4Association of Toll-like receptor gene polymorphisms with susceptibility to hepatitis B virus-related acute-on-chronic liver failure: a case–control studyCohort Study · 2026
5TLR3 rs3775291 C/T polymorphism is associated with elevated IFN-α level in asymptomatic HTLV-1 infection2025 · 2 citations

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