Concise Overview of Cancer Cell Biology, Metastasis and Death Mechanisms

In this article we study we review and compile data from the literature of the tumor cell biology, origin, therapeutics, metastatic mechanism and tumor-host interactions.Cancer originates through a sequence of somatic mutations in DNA that result in unrestrained cellular proliferation.Most of these differences require genuine sequence alterations in DNA (i.e.Mutations).They may arise as a consequence of random replication defects, exposure to carcinogens (e.g.radiation), or defective DNA repair machinery.Different drugs useful for the therapies of cancers are explained in a lucid manner.Carcinomas can invade local tissues and preform metastasis, that is distant spread by the lymphatic and haematogenous routes.