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June 20, 2024Kidney International ReportsOpen Access

APOL1 High-Risk Genotype is Not Associated With New or Worsening of Proteinuria or Kidney Function Decline Following COVID-19 Vaccination

Sarah Nystrom Karen Soldano Micki Rockett Somenath Datta Guojie Li Daniel Silas Melanie E. GarrettAllison E. Ashley‐Koch Opeyemi A. Olabisi

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Abstract

SARS-CoV-2 infection increases systemic inflammatory cytokines which act as a second-hit driver of Apolipoprotein L1 (APOL1)-mediated collapsing glomerulopathy. SARS-CoV-2 vaccination also increases cytokines. Recent reports of new glomerular disease in individuals with

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Nystrom et al. (2024) studied this question.

synapsesocial.com/papers/68e63f5cb6db6435875d0d04 https://doi.org/10.1016/j.ekir.2024.06.023

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