The biosensor is extremely important for the early diagnosis, drug discovery, healthcare, and clinical applications. Here we propose a unique LPG/FBG hybrid structure yielding ultra-narrow and high signal-to-noise ratio reflection resonances. It is the first time to report high order cladding-cladding mode coupling beyond core-core and core-cladding coupling. The proposed device has been exploited as optical biosensor for the detection of human haemoglobin achieving a high sensitivity. The proposed sensor can be further developed as a point-of-care device for portable and label-free biomedical diagnostic applications.
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Sun et al. (2024) studied this question.
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