Exploring Homoeopathic Potential Against Typhoid: Baptisia tinctoria, Rhus toxicodendron, and Eupatorium perfoliatum in growth Inhibition of Salmonella typhi – In-vitro study

Abstract Typhoid fever, caused by Salmonella typhi, is a global health issue with high morbidity and mortality rates, especially in low-income regions. The rise of antibiotic-resistant strains necessitates new treatment strategies. This study explores the potential of homoeopathic medicines, known for their safety and non-induction of resistance, as an alternative treatment. Three homoeopathic medicines, Rhus toxicodendron, Eupatorium perfoliatum, and Baptisia tinctoria, were tested for their inhibitory effects on S. typhi using the agar disc diffusion method. The medicines, along with a control antibiotic, ceftriaxone, were applied to agar plates with S. typhi cultures. All tested homoeopathic medicines showed inhibitory effects against S. typhi. Rhus toxicodendron Q and Baptisia tinctoria 200 CH showed significant inhibition zones of 16 mm and 14 mm, respectively. Baptisia tinctoria 30 CH and Eupatorium perfoliatum 30 CH also showed inhibitory effects, while ceftriaxone exhibited the largest inhibition zone. This study highlights the need for innovative treatments against antibiotic-resistant infections. It confirms the antimicrobial potential of homoeopathic medicines against S. typhi, suggesting a possible solution for this infectious disease. Further research is needed to assess their clinical effectiveness in managing typhoid fever.