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Multiparametric MRI assessment reveals graded microstructural damage near cerebrospinal fluid in multiple sclerosis, highlighting progressive tissue injury across cortical and deep gray matter.
A CSF-in gradient in cortical and thalamic gray matter (GM) damage has been found in multiple sclerosis (MS). We concomitantly explored the patterns of cortical, thalamic, and caudate microstructural abnormalities at progressive distances from CSF using a multiparametric MRI approach.
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Rubin et al. (2024) studied this question.
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