Prognostic indicators and management of severe acute pancreatitis

Severe acute pancreatitis (SAP) is defined according to clinicobiological, radiological, and evolutionary criteria. In this review, we discuss the main prognostic factors and propose a therapeutic approach based on recent literature. The treatment of SAP primarily involves resuscitation and intensive care, with surgery reserved as a secondary treatment in the event of complications or cases of biliary etiology. Despite advancements, the prognosis remains guarded for severe forms. A critical challenge in this emergency context is the early identification of markers that can guide patients with severe SAP to referent centers with multidisciplinary and specialized teams. These teams play a dual role: providing optimal acute-phase care and ensuring long-term monitoring due to potential functional consequences that may persist post-crisis.