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June 18, 2024Journal of Parkinson s DiseaseOpen Access

Serotonergic Regulation of Synaptic Dopamine Levels Mitigates L-DOPA-Induced Dyskinesia in a Mouse Model of Parkinson’s Disease

Yuan-Hao Chen Tung‐Tai Kuo Vicki Wang Pin-Wen Cheng Eagle Yi-Kung Huang Kuo‐Hsing Ma Nigel H. Greig Luis B. Tovar‐y‐Romo Barry J. Hoffer Kuan-Yin Tseng

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Abstract

The serotonin (5-HT) system can manipulate the processing of exogenous L-DOPA in the DA-denervated striatum, resulting in the modulation of L-DOPA-induced dyskinesia (LID).

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Cite This Study

Chen et al. (2024) studied this question.

synapsesocial.com/papers/68e643d5b6db6435875d52d6 https://doi.org/10.3233/jpd-240080

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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