Imagining with scattered light: wavefront shaping for fluorescence imaging in complex media

Wavefront shaping allows focusing and imaging at depth in disordered media such as biological tissues, exploiting the ability to control multiply scattered light. Many so-called guide-star mechanisms have been investigated to deliver light and image non-invasively, among which incoherent processes such as non-linear fluorescence feedback. However, the most common microscopy contrast mechanism, linear fluorescence, remains extremely challenging. I will discuss some of our recent works, exploiting signal processing and machine learning frameworks, to recover images behind scattering layers exploiting linear fluorescence.