In Vitro Pharmacognostic Evaluation of Laurus Nobilis Against Human Cancer Cells

In vitro antimitotic, and antioxidant activities of bay leaf extracts of Laurus nobilis were evaluated as a preliminary study for anticancer activity using the MTT assay. The crude Methanol, Ethyl acetate, Petroleum ether subsequent solvent fractions were employed in the study. y. In antimitotic assay, the methenol fraction showed strongest antimitotic activity with mitotic index. The antioxidant activity of Laurus nobilis and the isolated compounds was evaluated in vitro methods based on the free-radical scavenging properties of antioxidants. The Trolox equivalent antioxidant activity assay, in which Laurus nobilis showed the antioxidant activity in all extract but the best results, was found in aqueous extract as compared to others. The study concluded that the bay leaf extracts of Laurus nobilis can be used as a source of biologically active compounds with antimitotic, antiproliferative and antioxidant activities.