Epidemiological review uncovers potential links between HLA alleles and thyroid immune-related adverse events in patients, suggesting a genetic overlap with autoimmune disease risks.
Inherent variations in human leukocyte antigen (HLA) alleles have been revealed epidemiologically to influence the development of autoimmune diseases. HLA alleles may thus also be associated with the development of immune-related adverse events (irAEs), such as thyroid irAE.
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Sasaki et al. (2024) studied this question.
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