October 8, 2025Frontiers in GastroenterologyOpen Access

Bioinformatic analysis of the potential common pathogenic mechanisms for gastric precancerous lesions and Helicobacter pylori

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Authors

YLYi LiangNanjing Forestry University TJTiancai JiangChinese Academy of Sciences STSiyu TaoChinese Academy of Medical Sciences & Peking Union Medical College

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Implication

Bioinformatics analysis identifies seven hub genes linked to gastric precancerous lesions and H. pylori, suggesting potential shared pathways in cancer progression.

Key Points

The study identified 189 differentially expressed genes (DEGs) related to gastric precancerous lesions and Helicobacter pylori.
Seven hub genes were found to have high diagnostic value, indicating their potential in predicting disease occurrence.
Functional enrichment analysis highlighted pathways involving immune system regulation and leukocyte migration.
These findings may guide the identification of biomarkers and strategies to prevent gastric cancer development.

Cite This Study

Liang et al. (2025) studied this question.

synapsesocial.com/papers/68e6494525bc5bdb98713a5f https://doi.org/10.3389/fgstr.2025.1598916

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Implication

Bioinformatics analysis identifies seven hub genes linked to gastric precancerous lesions and H. pylori, suggesting potential shared pathways in cancer progression.

Bioinformatic analysis of the potential common pathogenic mechanisms for gastric precancerous lesions and Helicobacter pylori

Discussion

Member takes

Implication

Key Points

Cite This Study

Bioinformatic analysis of the potential common pathogenic mechanisms for gastric precancerous lesions and Helicobacter pylori

Discussion

Member takes

Implication

Key Points

Cite This Study

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