Antibiotics have been known to cause various drug adverse events. Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions that are considered off-target, including anaphylaxis, and organ-specific and severe cutaneous adverse reactions. Anaphylaxis can be mild to severe. Antibiotics can result in adverse drug reactions (ADRs) and hypersensitivity reactions (HSRs) through a variety of mechanisms. ADRs include any untoward medication effect experienced at normal therapeutic doses of the drug, and HSRs are ADRs that are immunologically mediated. Though any antibiotic can cause adverse drug reaction, severe anaphylaxis has rarely been reported with teicoplanin. We report here a case of severe anaphylaxis due to teicoplanin. The patient required medical intensive care support but recovered.
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Sharma et al. (2024) studied this question.
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