Introduction: Chronic Kidney Disease (CKD) is a major global health issue that gradually impairs kidney function, leading to systemic complications like cardiovascular diseases (CVD), which are signicantly more prevalent in CKD patients compared to the general population. This study aims to explore the changes in lipoprotein metabolism in CKD patients, highlighting how dyslipidemia, characterized by high triglycerides and altered HDL and LDL levels, contributes to increased cardiovascular morbidity and mortality in this group. Methods: This cross-sectional study evaluated the lipid proles of 50 adult CKD patients at a tertiary care teaching hospital in Navi Mumbai, analyzing correlations between CKD stages and lipid changes using SPSS, with a focus on maintaining patient anonymity and data condentiality during the 2022-23 data collection period. Results: The descriptive statistics for various biochemical parameters, showing signicant variability in fasting lipid prole, kidney function tests, and other parameters among the studied population. It reveals moderate to high variability in LDL, HDL, and triglycerides, as well as in markers of kidney function such as BUN, Creatinine, and urea, indicating potential health concerns that vary widely among individuals. Further, the frequency of normal and abnormal levels across these parameters, highlighting concerns such as a high prevalence of abnormal lipid levels and kidney function which could increase the risk for cardiovascular diseases and necessitate targeted interventions. Conclusion: The study highlights critical health risks due to abnormal lipid proles and kidney dysfunction among participants, highlighting the urgent need for targeted interventions to address prevalent cardiovascular risks and improve overall healthcare outcomes.
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Farooqui et al. (2024) studied this question.
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