Silene vulgaris (Moench) Garcke is among many plants that people worldwide use for its roots and leaves as a traditional medication. The target of the current research was to analyse the phytochemical contents of several extracts derived from the roots and leaves of S. vulgaris and assess their antioxidant properties. Colorimetric phytochemical assays conducted on S.vulgaris have verified the availability of diverse secondary compounds such as saponins, alkaloids, flavonoids, and polyphenols. The crude extract obtained by decocting the butanolic solution (Dec-nBA) of both roots and leaves exhibited the highest concentration of secondary metabolites, including polyphenols, flavonoids, and flavonol. The assessment of the plant's antioxidant properties was successfully conducted using the 2-Diphenyl-1-Picrylhydrazyl (DPPH) assay, the ferric reducing antioxidant power (FRAP) assay, and the total antioxidant capacity (TAC) assay. The DPPH antioxidant potential of S. vulgaris extracts indicates that Dec-nBA extract from the leaf is remarkably powerful than the other extracts, as evidenced by its half maximal inhibitory concentration (IC50) value of 320±0.1 ug/ml. Furthermore, the FRAP assay turned out to show that the same extract provided the greatest performance, exhibiting an IC50 value of 151.98±0.3 ug/ml. Overall, the leafy parts of S. vulgaris exhibited significantly greater antioxidant activity compared to the roots.
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Berrezig et al. (2024) studied this question.
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