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Large surface full-thickness burns pose a significant clinical challenge to the burn surgeon. Integra® dermal matrix has now been commercially available for more than 3 decades. Over this time, its role continues to evolve, and it remains an important tool in the hands of a burn surgeon. Integra® is now being successfully used in acute burn injury, chronic wounds, and reconstructive surgery. Successful outcomes, however, are predicated on a multitude of factors. This overview serves to provide a history of the device, review data and lessons learned, and provide an algorithm for success based on the experience of the authors.
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Mittal et al. (2024) studied this question.
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