Comparison of perinatal and neonatal outcomes of symptomatic pregnancy infected with SARS-CoV-2

Objective: In this study, maternal and neonatal outcomes of pregnant women with positive severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) RNA tests were evaluated according to their symptomatic status.The clinical progression of SARS-CoV-2-positive pregnant women and the effect of coronavirus disease-2019 (COVID-19) on newborns was investigated. Material and Methods:This retrospective cohort study was conducted at a tertiary pandemic hospital specializing in caring for pregnant women infected with SARS-CoV-2.We included patients with a positive SARS-CoV-2 polymerase chain reaction test at delivery, subdividing them into symptomatic and asymptomatic groups.Results: Two hundred and forty-nine patients were included in the study.The mean age of the pregnant women in the symptomatic group was higher than those in the asymptomatic group (p=0.001).The iatrogenic preterm birth rates in the symptomatic and asymptomatic groups were 43.37% and 8.43%, respectively (p<0.001).Cesarean section rate was higher in symptomatic group (p=0.01).Maternal death was significantly higher in symptomatic pregnant women (p<0.001).The neonatal intensive care unit admission rate was higher in symptomatic pregnant women (p<0.001). Conclusion:The maternal and fetal outcomes for mothers with symptomatic infections tend to be worse, highlighting the importance of careful management, good follow-up and the advisability of closer monitoring.(