A Prospective Study of Cigarette Smoking and Risk of 10-Years Incidence of Hypertension in men aged 20-74 years old; Yazd Healthy Heart Cohort Study (YHHC)

Abstract The effects of cigarette smoking on blood pressure are complex, with evidence that smoking increases acute increase in blood pressure (BP), heart rate, risk of renovascular, malignant, and masked hypertension. We evaluated smoking status in phase I and hypertension incidence in males after 10 years using YHHC (Yazd Healthy Heart Cohort Study) data. All of normotensives participants enrolled the analysis. Univariate analysis was performed via Chi -square and student T tes and we employed a multivariable logistic regression model with the "backward" method to assess the risk of hypertension associated with smoking status while adjusting for other risk factors. out of total 446 male follow –uped during 10-years, 37 new case(31.9%) developed hypertension incidence in smoker men at the baseline. We found in Multivariate-adjusteda(aOR = 0.52,95%CI(0.29–0.94,P = 0.032) and Multivariate-adjustedb(aOR = 0.58,95%CI(0.31–1.08,P = 0.089) withStepwise Model selection variable Cigarette Smoking history don’t increase 10-years hypertension.we observed history of smoking associated with decrease hypertension incidence.