Proximal Femoral Cortical Thickness Index as a Predictor of Osteoporosis in Women Aged Over 65 Years Old

Background: Osteoporosis is a systemic condition characterized by loss of bone mass. The gold standard for diagnosing osteoporosis is bone mineral density (BMD) examination. Measurement of proximal femoral Cortical Thickness Index (CTI) can be considered as a predictor of osteoporosis. This research was conducted to prove proximal femoral CTI as a predictor of osteoporosis in women aged over 65 years. Methods: This research is a cross-sectional study including a correlation test, mean difference test, and diagnostic test for numeric variables. The study population were women aged over 65 years who underwent x-ray and BMD examination at Prof. Dr. IGNG Ngoerah General Hospital from 2021 until October 2023. Samples were taken by consecutive sampling. The subjects were measured for proximal femoral CTI, correlation analysis, mean difference between two groups, and receiver operating characteristic (ROC). Results: Among 34 research subjects, a weak and significant correlation was found between the proximal femoral CTI and BMD (r = −0.387, p = 0.024). The mean of CTI in the osteoporosis group was lower compared with the group without osteoporosis (p = 0.021). The ability of CTI to predict osteoporosis is quite good (AUC > 0.7). The CTI cut-off point of <0.62 is not proven as a predictor of osteoporosis. The most optimal cut-off point of proximal femoral CTI as a predictor of osteoporosis is <0.57 with 70.59% sensitivity, 76.47% specificity, 82.4% positive predictive value (PPV), and 58.8% negative predictive value (NPV). Conclusion: Proximal femoral CTI can be considered a predictor of osteoporosis in women aged over 65 years old.