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June 12, 2024ToxicologyOpen Access

Legacy and alternative per- and polyfluoroalkyl substances (PFAS) alter the lipid profile of HepaRG cells

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LKLackson KashobweFSFaezeh SadrabadiLBLars Brunken

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Kashobwe et al. (2024) studied this question.

synapsesocial.com/papers/68e64f8fb6db6435875e0715https://doi.org/10.1016/j.tox.2024.153862
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Perfluoroalkyl Sulfonates Cause Alkyl Chain Length–Dependent Hepatic Steatosis and Hypolipidemia Mainly by Impairing Lipoprotein Production in APOE*3-Leiden CETP Mice2011 · 159 citations
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  3. 3Evaluation of the Chronic Toxicity and Carcinogenicity of Perfluorohexanoic Acid (PFHxA) in Sprague-Dawley Rats2014 · 87 citations
  4. 4To which extent are per-and poly-fluorinated substances associated to metabolic syndrome?2021 · 16 citations
  5. 5Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease2021 · 295 citations