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June 12, 2024Cardiovascular DiabetologyOpen Access

Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i

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Authors

MHMakoto HaradaJAJonathan AdamMCMarcela Covic

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Cite This Study

Harada et al. (2024) studied this question.

synapsesocial.com/papers/68e650a7b6db6435875e0fffhttps://doi.org/10.1186/s12933-024-02288-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i2024
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  3. 3Effects of SGLT2 Inhibitors with and without Metformin in High-Risk, Treatment-Naïve Patients with Diabetes2024 · 2 citations
  4. 4Metabolomics Insights into the Benefits of SGLT2 Inhibitors in Type 2 Diabetes2025 · 1 citations
  5. 5Novel mechanism whereby metformin improves glucose homeostasis: TXNIP–GLUT1 axis modulation enhances intestinal glucotonic effects2025 · 5 citations