⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

June 12, 2024Journal of Pharmacology and Experimental TherapeuticsOpen Access

AAV9-Mediated Intra-Striatal Delivery ofGNAO1Reduces Hyperlocomotion inGnao1Heterozygous R209H Mutant Mice

Alex J. Roy Jeffrey R. Leipprandt Joseph R. Patterson Anna C. Stoll Christopher J. Kemp Zaipo-Tcheisian D. Oula Tyler Mola Ana Rita Batista Caryl E. Sortwell Miguel Sena‐Esteves Richard R. Neubig

View Full Paper

Ask AI

Bookmark

Share

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Abstract

Mutations in the

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Roy et al. (2024) studied this question.

synapsesocial.com/papers/68e651bbb6db6435875e1a87 https://doi.org/10.1124/jpet.124.002117

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1AAV9-mediated Intra-striatal Delivery of<i>GNAO1</i>Reduces Hyperlocomotion in<i>Gnao1</i>Heterozygous R209H Mutant Mice2024
2Gene supplementation therapy restores motor deficits in Gnao1[C215Y] mice and proves broad efficacy in C. elegans modelOriginal Research · 2026 · 2 citations
3i.c.v. delivery of AAV9-synapsin-promoted caveolin-1 attenuates neuromuscular deficits and neuromuscular degeneration in hSOD1G93A miceOriginal Research · 2026
4Neonatal gene therapy with AAV2/8-LSPhGAA improves hypertrophic cardiomyopathy in the Gaac.1826dupA knock-in murine modelpreclinical · 2026
5Gnao1 is a molecular switch that regulates the Rho signaling pathway in differentiating neurons2024 · 9 citations