Circulating levels of omega-3 PUFA and their erythrocyte membrane levels (omega-3 index) inversely associate with cardiovascular events.As flaxseed oil and fish oil have complementary cardioprotective benefits, the combined effect of a daily supplementation of ALA (868.98 mg), EPA (358.2 mg) and DHA (238.4 mg) was studied in pre-obese, mild hypercholesterolemic women using a pretest, post-test research design.30 premenopausal and 30 postmenopausal subjects (equally assigned to control and test groups) underwent two week baseline, 60 days study/supplementation and two week withdrawal (test group alone) periods.The combined supplementation was significantly hypocholesterolemic, hypotensive, anti-inflammatory and obesity-lowering alongside improving omega-3 index.
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Sunder et al. (2024) studied this question.
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