Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 11, 2024Nature CommunicationsOpen Access

Non-viral DNA delivery and TALEN editing correct the sickle cell mutation in hematopoietic stem cells

View Full Paper
Ask AI
Bookmark
Share

Authors

AMArianna MoianiGLGil LetortSLSabrina Lizot

Discussion

Loading...

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Moiani et al. (2024) studied this question.

synapsesocial.com/papers/68e6541cb6db6435875e2d99https://doi.org/10.1038/s41467-024-49353-3
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Multiplex CRISPR/Cas9 genome editing in hematopoietic stem cells for fetal hemoglobin reinduction generates chromosomal translocations2021 · 51 citations
  2. 2BCL-XL expression is essential for human erythropoiesis and engraftment of hematopoietic stem cells2020 · 62 citations
  3. 3Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates2012 · 1,197 citations
  4. 4Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality2019 · 65 citations
  5. 5Genotoxic effects of base and prime editing in human hematopoietic stem cells2023 · 228 citations