Preclinical evaluation reveals the structural and functional profile of pegmolesatide, suggesting enhanced therapeutic utility for erythropoiesis stimulation.
Pegmolesatide, a synthetic, polyethylene-glycolylated, peptide-based erythropoiesis-stimulating agent (ESA), has been recently approved in China. Pegmolesatide is derived from the structure of endogenous erythropoietin (EPO), a natural product in mammals. This study compared the
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