June 10, 2024AgingOpen Access

Disulfidptosis-related lncRNAs signature predicting prognosis and immunotherapy effect in lung adenocarcinoma

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Patient survival in lung adenocarcinoma correlates closely with a novel disulfidptosis risk score, distinguishing high-risk individuals with distinct immune infiltration.
Ten prognostic lncRNAs selected from 108 candidates accurately stratify clinical risk, showing significant survival differences and elevated sensitivity to cisplatin.
Cox regression and immune infiltration profiling reveal altered immune checkpoints, highlighting disulfidptosis as a viable target for personalized lung adenocarcinoma therapy.

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Implication

Transcriptomic analysis demonstrates a disulfidptosis-related lncRNA prognostic signature in lung adenocarcinoma, highlighting novel predictive biomarkers for targeted immunotherapy.

Cite This Study

Hong et al. (2024) studied this question.

synapsesocial.com/papers/68e6566db6db6435875e5206 https://doi.org/10.18632/aging.205911

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Implication

Transcriptomic analysis demonstrates a disulfidptosis-related lncRNA prognostic signature in lung adenocarcinoma, highlighting novel predictive biomarkers for targeted immunotherapy.

Disulfidptosis-related lncRNAs signature predicting prognosis and immunotherapy effect in lung adenocarcinoma

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Implication

Cite This Study

Disulfidptosis-related lncRNAs signature predicting prognosis and immunotherapy effect in lung adenocarcinoma

Key Points

Discussion

Implication

Cite This Study

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