This work presents the conjugation of tumor-specific targeting ligands, folic acid, onto the surface of Conjugated Polymer Nanoparticles (CPNs) based on a common solar cell material (PTB7), which exhibits low nonspecific cell adhesion. The goal is to create near-infrared (NIR)-active theranostic probes capable of specifically targeting cancer cells. By adjusting the proportion of folic acid during the synthesis process, the targeting efficiency and singlet oxygen generation efficiency of the nanoparticles can be finely tuned.
No takes yet. Share an insight, caveat, or question.
Zhao et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: