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June 7, 2024Multiple Sclerosis Journal

Enlarged perivascular spaces are associated with brain microangiopathy and aging in multiple sclerosis

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Abstract

Growing evidence links brain-MRI enlarged perivascular spaces (EPVS) and multiple sclerosis (MS), but their role remains unclear.

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Cite This Study

Borrelli et al. (2024) studied this question.

synapsesocial.com/papers/68e65999b6db6435875e8d35 https://doi.org/10.1177/13524585241256881

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Enlarged perivascular spaces in the basal ganglia are associated with arteries not veins2024 · 17 citations
2CAA-related enlarged perivascular spaces are associated with abnormal angioarchitecture in human brain tissue: A key role for white matter atrophy?2025 · 1 citations
3“Mind the Gap”—enlarged perivascular spaces as a potential magnetic resonance imaging biomarker of impaired glymphatic clearance in brain disordersReview · 2026
4The Significance and Mechanism of Cerebral Enlarged Perivascular Space in Amyotrophic Lateral Sclerosis2025
5Enlarged Perivascular Spaces in the Basal Ganglia Surround Arteries, not Veins2024