Extraction, characterization and optimization of phenolic compounds from Siam weed (Chromolaena odorata)

In this study, methanol and water were used as solvents to extract the phenolic compounds from Siam weed. The qualitative and quantitative analyses of the extract were performed to determine the suitability of the weed in the treatment of certain diseases. The process variables for the extraction were optimized. The results show that methanol produced higher quantity of bioactive components than water. The qualitative analysis show that Siam weed contains many bioactive compounds. The quantitative results show that it contains phenolic 52.3 Ggae/100 g, Tannin 12.3%, Alkaloids 5.5 %, Steroids 0.6%, Flavonoids 0.6 % and Glycosides 0.3 %. The optimum yield of 52.32Ggae/100g phenolic compound is obtained at Time of 1.88 hrs. Temp. 45 ℃ and Dosage 2.50 g.