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June 6, 2024Poultry ScienceOpen Access

Canthin-6-one analogs block Newcastle disease virus proliferation via suppressing the Akt and ERK pathways

Chongyang Wang Ting Wang Jiangkun Dai Han Yu Ruochen Hu Na Li Zengqi Yang Junru Wang

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Abstract

Newcastle disease virus, a member of the Paramyxoviridae family, causes significant economic losses in poultry worldwide. To identify novel antiviral agents against NDV, 36 canthin-6-one analogs were evaluated in this study. Our data showed that 8 compounds exhibited excellent inhibitory effects on NDV replication with IC

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Cite This Study

Wang et al. (2024) studied this question.

synapsesocial.com/papers/68e65d18b6db6435875eb632 https://doi.org/10.1016/j.psj.2024.103944

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